Greensboro Founded in 1786, is the county seat and hometown of Lake Oconee. Selected in 1997 as one of the first five Better HomeTown Communities in Georgia, it is steeped in southern history and tradition, rich with elegant antebellum homes and churches. Greensboro's "Gaol" is one of the oldest penal structures in Georgia and the Greene County Courthouse is one of the finest examples of stately revival architecture in Georgia. The historical buildings in the downtown area are filled with enticing wares, featuring antiques, clothing, gifts, and jewelry.

Union Point Developed from a railroad junction in 1834, Union Point is the home of Chipman-Union Hosiery Mill, a historic mill complex with 20 buildings, built in the late 1800's. Known for its fine Victorian residential and commercial structures, it also features one of the state's oldest churches, Bethesda Baptist, organized in 1785.

White Plains Named for the grayish-white sandy soil in the county, White Plains is occupied by several late 1800 Gothic Revival homes. It is considered home of Holcomb's Barbecue.

Siloam Originally named Smyrna, the town was settled in the early part of the 19th century. Home of Nathanael Greene Academy, Siloam also has several sites listed on the National Register of Historic Places and has been proposed as a national Historic District. Siloam has five churches two Baptist, two Methodist, and Presbyterian.

Woodville This village located five miles north of Union Point is said to have been given it's name because here in the early 1800's the trains loaded up with wood. This community features several sites, such as the old schoolhouse and city hall, which are listed on the National Register of Historic Places.